BYSTOLIC is a beta-adrenergic blocking agent indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

Most common adverse reactions:
• Headache, fatigue

• CYP2D6 enzyme inhibitors may increase nebivolol levels.
• Reserpine or clonidine may produce excessive reduction of sympathetic activity.
• Both digitalis glycosides and β-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can increase the risk of bradycardia
• Verapamil- or diltiazem-type calcium channel blockers may cause excessive reductions in heart rate, blood pressure, and cardiac contractility.

• Acute exacerbation of coronary artery disease upon cessation of therapy: Do not abruptly discontinue.
• Diabetes: Monitor glucose as β-blockers may mask symptoms of hypoglycemia.