Medications
Oxcarbazepine - Trileptal, OxtellarXR
Uses
Side Effects
Interactions
Precautions
Uses
Oxtellar XR® is indicated for the treatment of partial-onset seizures in patients 6 years of age and older
Side Effects
Most commonly observed (≥5% and more frequent than placebo) adverse reactions in adults were dizziness, somnolence, headache, balance disorder, tremor, vomiting, diplopia, asthenia, and fatigue.
Adverse reactions in pediatric patients are similar to those seen in adult patients.
Interactions
- Phenytoin, Carbamazepine, and Phenobarbital: Coadministration decreased blood levels of an active metabolite of Oxtellar XR® : Greater dosage of Oxtellar XR® may be required..
- Oral Contraceptives: Advise patients that Oxtellar XR® may decrease the effectiveness of hormonal contraceptives. Additional non-hormonal forms of contraception are recommended.
Precautions
- Hyponatremia: Monitor sodium as recommended.
- Cross Hypersensitivity Reaction to Carbamazepine: Discontinue immediately if hypersensitivity occurs
- Serious Dermatological Reactions: Discontinue if observed
- Suicidal Behavior and Ideation: Monitor for symptoms
- Withdrawal of Oxtellar XR® : Withdrawal gradually
- Drug Reaction with Eosinophilia and Systemic symptoms (DRESS)/Multi-Organ Hypersensitivity: Discontinue if suspected
- Hematologic Reactions: Discontinue if suspected
- Risk of Seizure Aggravation: Discontinue if occurs
